Table 5.
Genotype and allele frequencies of the miR-125a polymorphism in patients with Graves' disease (GD), Hashimoto's disease (HD) and in control subjects
| Control | All patients with GD | All patients with HD | ||||
|---|---|---|---|---|---|---|
| miR-125a | CC | 87 (73·73%) | 122 (78·71%) | n.s. | 127 (84·11%) | 0·037 |
| rs12976445 | CT | 31 (26·27%) | 31 (20%) | 24 (15·89%) | ||
| TT | 0 (0%) | 2 (1·29%) | 0 (0%) | |||
| CC + CT | 118 (100%) | 153 (98·71%) | n.s. | 151 (100%) | n.s. | |
| TT | 0 (0%) | 2 (1·29%) | 0 (0%) | |||
| CC | 87 (73·73%) | 122 (78·71%) | n.s. | 127 (84·11%) | 0·036 | |
| CT + TT | 31 (26·27%) | 33 (21·29%) | 24 (15·89%) | |||
| C allele | 205 (86·86%) | 275 (88·71%) | n.s. | 278 (92·05%) | 0·049 | |
| T allele | 31 (13·14%) | 35 (11·29%) | 24 (7·95%) | |||
n.s. = not significant.