Table 6.
Genotype and allele frequencies of the miR-125a polymorphism in patients with Graves' disease (GD), Hashimoto's disease (HD)
| GD | HD | ||||||
|---|---|---|---|---|---|---|---|
| Intractable | In remission | Severe | Mild | ||||
| miR-125a | CC | 51 (85%) | 30 (66·67%) | n.s. | 48 (81·36%) | 36 (87·80%) | n.s. |
| rs12976445 | CT | 8 (13·33%) | 14 (31·11%) | 11 (18·64%) | 5 (12·20%) | ||
| TT | 1 (1·67%) | 1 (2·22%) | 0 (0%) | 0 (0%) | |||
| CC + CT | 59 (98·33%) | 44 (97·78%) | n.s. | 59 (100%) | 41 (100%) | n.s. | |
| TT | 1 (1·67%) | 1 (2·22%) | 0 (0%) | 0 (0%) | |||
| CC | 51 (85%) | 30 (66·67%) | 0·027 | 48 (81·36%) | 36 (87·80%) | n.s. | |
| CT + TT | 9 (15%) | 15 (33·33%) | 11 (18·64%) | 5 (12·20%) | |||
| C allele | 110 (91·67%) | 74 (82·22%) | 0·040 | 107 (90·68%) | 77 (93·90%) | n.s. | |
| T allele | 10 (8·33%) | 16 (17·78%) | 11 (9·32%) | 5 (6·10%) | |||
n.s. = not significant.