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. 2014 Oct 1;178(2):342–352. doi: 10.1111/cei.12403

Fig. 1.

Fig. 1

Enzyme-linked immunospot assay assay for detection of interleukin (IL)-17- and interferon (IFN)-γ-producing cells in bronchoalveolar lavage (BAL) samples. (a) IL-17- and IFN-γ-producing cells in bronchoalveolar lavage (BAL) samples from patients with and without Löfgren's syndrome after stimulation with Mycobacterium tuberculosis catalase-peroxidase (mKatG), PHA or anti-CD3. (b) Paired analysis of IL-17- and IFN-γ-producing cells reacting to mKatG in BAL samples from patients with or without Löfgren's syndrome. (c) Correlation of neutrophil percentage and number of mKatG-reactive IL-17-producing cells in BAL fluid of sarcoidosis patients with Löfgren's syndrome. Graphs show mean numbers of spots per 106 cells per well after deduction of background. The correlations were analysed using Spearman's rank test (r = 0·84; P < 0·01; *P < 0·05; ***P < 0·001).