. Author manuscript; available in PMC: 2015 Aug 1.

Published in final edited form as: Neurol Clin. 2014 Aug;32(3):569–vii. doi: 10.1016/j.ncl.2014.04.008

BOX 23. DIFFERENTIAL DIAGNOSIS OF CK ELEVATION.

Myopathies	Neuropathies
Carrier state (dystrophinopathies)	Charcot-Marie Tooth
Channelopathies	Guillain Barre syndrome
Congenital myopathies
Drug/toxin-induced	Others
Inflammatory myopathies	“Idiopathic hyperCKemia”
Metabolic myopathies	Increased muscle mass
Muscular dystrophies	Hypothyroidism/hypoparathyroidsim
Muscular dystrophies	Medications
Motor neuron diseases	Race
Amyotrophic lateral sclerosis	Sex
Post-polio syndrome	Strenuous exercise
Spinal muscular atrophy	Surgery
Spinal muscular atrophy	Trauma (EMG studies, IM, or SQ injections)