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. Author manuscript; available in PMC: 2015 Jan 1.
Published in final edited form as: J Toxicol Environ Health A. 2014;77(13):751–766. doi: 10.1080/15287394.2014.892446

Fig. 3. APOE is a top upstream regulator influencing altered gene expression in PM10-treated mice.

Fig. 3

APOE was identified as an upstream regulator of many of the genes induced by PM10. Most of the genes affected by this regulator are up-regulated and only a few are down-regulated.