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Select relationships between entities in the EAE domain model. (a) The use of UML class diagram composition relationships depicting mutually exclusive expression of MHC : peptide complexes on cells. (b) The relationship between type 1 cytokines and CNS macrophages. The cardinalities have been labelled ‘Θ’ and ‘Ω’ to facilitate discussion in the text. (c) The relationship that a CD4Th cell has in producing additional instances of itself.
