Table 5.
Remaining lifetime risks of first incident manifestation of hard atherosclerotic cardiovascular disease by age
| Age (years) and manifestation | Lifetime risk (%)* (95% CI) | P value | Excess events per 1000 women† | |
|---|---|---|---|---|
| Men | Women | |||
| Age 55: | ||||
| No of people | 3293 | 5126 | — | — |
| Hard atherosclerotic cardiovascular event | 43.2 (40.7 to 45.6) | 38.1 (36.2 to 40.1) | <0.001 | −51 |
| Hard coronary heart disease‡ | 23.5 (21.4 to 25.6) | 14.4 (13.0 to 15.8) | <0.001 | −91 |
| Non-haemorrhagic stroke | 17.8 (15.8 to 19.7) | 22.5 (20.8 to 24.2) | <0.001 | 48 |
| Other atherosclerotic cardiovascular death§ | 1.9 (1.3 to 2.6) | 1.2 (0.8 to 1.6) | 0.037 | −7 |
| Age 65: | ||||
| No of people | 3159 | 5003 | — | — |
| Hard atherosclerotic cardiovascular event | 40.3 (38.0 to 42.7) | 37.8 (35.8 to 39.7) | 0.050 | −26 |
| Hard coronary heart disease‡ | 20.8 (18.8 to 22.7) | 13.7 (12.3 to 15.1) | <0.001 | −70 |
| Non-haemorrhagic stroke | 17.7 (15.8 to 19.5) | 22.8 (21.0 to 24.5) | <0.001 | 51 |
| Other atherosclerotic cardiovascular death§ | 1.9 (1.3 to 2.6) | 1.3 (0.8 to 1.7) | 0.057 | −6 |
| Age 75: | ||||
| No of people | 1934 | 3560 | — | — |
| Hard atherosclerotic cardiovascular event | 35.5 (32.7 to 38.3) | 36.2 (34.1 to 38.4) | 0.34 | 7 |
| Hard coronary heart disease‡ | 16.8 (14.6 to 18.9) | 11.9 (10.5 to 13.4) | <0.001 | −48 |
| Non-haemorrhagic stroke | 16.7 (14.5 to 18.8) | 22.9 (21.0 to 24.8) | <0.001 | 62 |
| Other atherosclerotic cardiovascular death§ | 2.1 (1.3 to 2.9) | 1.4 (0.9 to 1.9) | 0.093 | −6 |
| Age 85: | ||||
| No of people | 594 | 1619 | — | — |
| Hard atherosclerotic cardiovascular event | 31.4 (26.9 to 35.8) | 31.6 (28.9 to 34.4) | 0.46 | 3 |
| Hard coronary heart disease‡ | 14.1 (10.8 to 17.4) | 10.3 (8.5 to 12.1) | 0.023 | −38 |
| Non-haemorrhagic stroke | 15.9 (12.4 to 19.4) | 20.2 (17.8 to 22.5) | 0.026 | 42 |
| Other atherosclerotic cardiovascular death§ | 1.3 (0.3 to 2.4) | 1.2 (0.5 to 1.8) | 0.41 | −1 |
*Adjusted for competing non-atherosclerotic death among men and women at different ages.
†Excess risk computed as absolute difference in remaining lifetime risk between men and women.
‡Hard coronary heart disease=myocardial infarction or death from coronary heart disease.
§Other atherosclerotic cardiovascular death=all atherosclerotic cardiovascular mortality other than fatal coronary heart disease or non-haemorrhagic stroke.