Table 2.

Wigglesworthia genes displaying significant differential expression in trypanosome infected vs. non-infected flies, 10 days post-infected blood meal uptake.

Gene symbols	Expression	GenBank	Name
mreB	Down	WIGMOR_0141__mreB	Family actin-like cell wall component
lolE	Down	WIGMOR_0108__lolE	Membrane component of an ABC superfamily outer membrane-specific lipoprotein transporter
	Down	WIGMOR_0238	tRNA
	Down	WIGMOR_0236	Translation elongation factor Tu
yadG	Down	WIGMOR_0498__yadG	Putative ATP-binding component of an ABC superfamily transporter
	Down	WIGMOR_0160	tRNA
htpX	Down	WIGMOR_0111__htpX	Putative endopeptidase
accD	Down	WIGMOR_0463__accD	Acetyl-CoA carboxylase carboxyl transferase, beta subunit
kdsA	Down	WIGMOR_0424__kdsA	3-deoxy-D-manno-octulosonate 8-phosphate synthase
rplP	Down	WIGMOR_0199__rplP	50S ribosomal protein L16
clpX	Down	WIGMOR_0629__clpX	ATPase and specificity subunit of ClpX-ClpP ATP-dependent serine protease
secA	Down	WIGMOR_0585__secA	Preprotein translocase subunit, ATPase
hslV	Down	WIGMOR_0501__hslV	Peptidase component of the HslUV protease
	Down	WIGMOR_0369	tRNA
	Down	WIGMOR_0435	tRNA
rpsC	Down	WIGMOR_0200__rpsC	30S ribosomal protein S3
flgE	Down	WIGMOR_0044__flgE	Flagellar hook protein
gmk	Down	WIGMOR_0358__gmk	Guanylate kinase
nusG	Down	WIGMOR_0234__nusG	Transcription termination factor
yadG	Down	WIGMOR_0498__yadG	Putative ATP-binding component of an ABC superfamily transporter
sucB	Down	WIGMOR_0344__sucB	Dihydrolipoyltranssuccinase
pgk	Down	WIGMOR_0469__pgk	Phosphoglycerate kinase
mraW	Down	WIGMOR_0572__mraW	S-adenosyl-dependent methyltransferase
mreB	Down	WIGMOR_0141__mreB	Family actin-like cell wall component
acpP	Down	WIGMOR_0097__acpP	Acyl carrier protein (ACP)
mdlB	Down	WIGMOR_0567__mdlB	Putative ATP-binding component of multidrug ABC transporter
cysS	Down	WIGMOR_0538__cysS	Cysteinyl-tRNA synthetase
leuS	Down	WIGMOR_0615__leuS	Leucyl-tRNA synthetase
nusG	Down	WIGMOR_0234__nusG	Transcription termination factor
mreB	Down	WIGMOR_0141__mreB	Family actin-like cell wall component
atpA	Down	WIGMOR_0006__atpA	F1 sector of membrane-bound ATP synthase, alpha subunit
nadA	Down	WIGMOR_0624__nadA	Quinolinate synthase subunit A
bioA	Down	WIGMOR_0307__bioA	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase
	Down	WIGMOR_0549	tRNA
	Down	WIGMOR_0558	tRNA
ftsA	Down	WIGMOR_0582__ftsA	Cell division protein
fbaA	Down	WIGMOR_0468__fbaA	Fructose-bisphosphate aldolase
atpD	Down	WIGMOR_0008__atpD	F1 sector of membrane-bound ATP synthase, beta subunit
flhC	Down	WIGMOR_0034__flhC	Family flagellar transcriptional activator
alaS	Down	WIGMOR_0548__alaS	Alanyl-tRNA synthetase
	Down	WIGMOR_0128	tRNA
proS	Down	WIGMOR_0145__proS	Prolyl-tRNA synthetase
rpsQ	Down	WIGMOR_0197__rpsQ	30S ribosomal protein S17
	Down	WIGMOR_0458	tRNA
	Down	WIGMOR_0134	16S ribosomal RNA
	Up	WIGMOR_0310	ncRNA
ribB	Up	WIGMOR_0545__ribB	3,4-dihydroxy-2-butanone-4-phosphate synthase
	Up	WIGMOR_0310	ncRNA
pnp	Up	WIGMOR_0564__pnp	Polynucleotide phosphorylase/polyadenylase
gyrB	Up	WIGMOR_0018__gyrB	DNA gyrase subunit B
rpsK	Up	WIGMOR_0183__rpsK	30S ribosomal protein S11
pepA	Up	WIGMOR_0300__pepA	Aminopeptidase A
flhD	Up	WIGMOR_0033__flhD	Family flagellar transcriptional activator
skp	Up	WIGMOR_0382__skp	Periplasmic chaperone
rpoH	Up	WIGMOR_0076__rpoH	RNA polymerase, sigma 32 (sigma H) factor
hemL	Up	WIGMOR_0077__hemL	Glutamate-1-semialdehyde aminotransferase
panB	Up	WIGMOR_0311__panB	3-methyl-2-oxobutanoate hydroxymethyltransferase
groS	Up	WIGMOR_0520__groS	Cpn10 chaperonin GroES, small subunit of GroESL
groL	Up	WIGMOR_0521__groL	Cpn60 chaperonin GroEL, large subunit of GroESL
truA	Up	WIGMOR_0464__truA	tRNA pseudouridine synthase A
sufS	Up	WIGMOR_0410__sufS	PLP-dependent selenocysteine lyase
prlC	Up	WIGMOR_0367__prlC	Oligopeptidase A
rlmB	Up	WIGMOR_0605__rlmB	23S rRNA Gm2251-methyltransferase
pykA	Up	WIGMOR_0648__pykA	Pyruvate kinase II

Wigglesworthia genes with significant differential expression, p < 0.05.