Table 3.
Wigglesworthia genes displaying significant differential expression in trypanosome-infected vs. non-infected flies, 20 days post-infected blood meal uptake.
| Gene symbols | Expression | GenBank | Name |
|---|---|---|---|
| cls | Down | WIGMOR_0400__cls | Cardiolipin synthase 1 |
| rpoC | Down | WIGMOR_0228__rpoC | RNA polymerase, beta prime subunit |
| aroA | Down | WIGMOR_0272__aroA | 3-phosphoshikimate 1-Carboxyvinyltransferase |
| flgC | Down | WIGMOR_0042__flgC | Flagellar component of cell-proximal portion of basal-body rod |
| yoaE | Down | WIGMOR_0112__yoaE | Hypothetical protein |
| alaS | Down | WIGMOR_0548__alaS | Alanyl-tRNA synthetase |
| asnS | Down | WIGMOR_0515__asnS | Asparaginyl tRNA synthetase |
| purF | Down | WIGMOR_0460__purF | Amidophosphoribosyltransferase |
| thiE | Down | WIGMOR_0249__thiE | Thiamin phosphate synthase |
| yadG | Down | WIGMOR_0498__yadG | Putative ATP-binding component of an ABC superfamily transporter |
| fusA | Down | WIGMOR_0032__fusA | GTP-binding protein chain elongation factor EF-G |
| groL | Down | WIGMOR_0521__groL | Cpn60 chaperonin GroEL, large subunit of GroESL |
| metG | Down | WIGMOR_0214__metG | Methionyl-tRNA synthetase |
| gpmA | Down | WIGMOR_0568__gpmA | Phosphoglyceromutase |
| nadA | Up | WIGMOR_0624__nadA | Quinolinate synthase subunit A |
| thiH | Up | WIGMOR_0253__thiH | Thiamin biosynthesis ThiGH complex subunit |
| pgi | Up | WIGMOR_0144__pgi | Glucosephosphate isomerase |
| Up | WIGMOR_0290 | tRNA | |
| Up | WIGMOR_0147 | tRNA | |
| rpsB | Up | WIGMOR_0374__rpsB | 30S ribosomal protein S2 |
| pepA | Up | WIGMOR_0300__pepA | Aminopeptidase A |
| pheS | Up | WIGMOR_0089__pheS | Phenylalanine tRNA synthetase subunit alpha |
| hns | Up | WIGMOR_0399__hns | Global DNA-binding transcriptional dual regulator H-NS |
| sufA | Up | WIGMOR_0406__sufA | Fe-S cluster assembly protein |
| Up | WIGMOR_0092 | Ribonuclease E | |
| ahpC | Up | WIGMOR_0270__ahpC | Alkyl hydroperoxide reductase C22 protein |
| leuS | Up | WIGMOR_0615__leuS | Leucyl-tRNA synthetase |
| rnt | Up | WIGMOR_0432__rnt | Ribonuclease T (RNase T) |
| sufA | Up | WIGMOR_0406__sufA | Fe-S cluster assembly protein |
| pyrG | Up | WIGMOR_0413__pyrG | CTP synthetase |
| yidC | Up | WIGMOR_0013__yidC | Membrane insertion protein |
| rpoH | Up | WIGMOR_0076__rpoH | RNA polymerase, sigma 32 (sigma H) Factor |
| ruvC | Up | WIGMOR_0122__ruvC | Endonuclease component of RuvABC resolvasome |
| nrdF | Up | WIGMOR_0676__nrdF | Ferritin-like ribonucleoside-diphosphate reductase 2, beta subunit |
| bamA | Up | WIGMOR_0381__bamA | Outer membrane beta-barrel protein assembly factor |
| sufC | Up | WIGMOR_0408__sufC | Fe-S cluster assembly transport protein |
| skp | Up | WIGMOR_0382__skp | Periplasmic chaperone |
| gshA | Up | WIGMOR_0534__gshA | Gamma-glutamate-cysteine ligase |
| ftsY | Up | WIGMOR_0075__ftsY | Signal recognition particle protein |
Wigglesworthia genes with significantl differential expression, p < 0.05.