Table 4.

Enriched Gene Ontology terms of differentially expressed genes^a in trypanosome-stimulated vs. non-stimulated flies, 3 days post-blood meal uptake.

GO accession	GO Termb	p-Value	Corrected p-valuec	Wigglesworthia genes
GO:0044267	Cellular protein metabolic process	6.505E-4	0.2539	rpsK, rplP, rpsC, rplB, fmt, rpsG, fusA, rpsR, groS, groL, rpsI, infC
GO:0030554	Adenyl nucleotide binding	7.432E-4	0.2539	groS, groL, ftsH, secA
GO:0032559	Adenyl ribonucleotide binding	7.432E-4	0.2539	groS, groL, ftsH, secA
GO:0043170	Macromolecule metabolic process	2.837E-4	0.2539	rpsK, rplP, rpsC, rplB, ksgA, rpoC, fmt, rpsG, fusA, rpoZ, recB, groS, groL, ftsH, rpsI, rnhA, rpoH, infC, rpsR
GO:004328
GO:0005524	ATP binding	7.432E-4	0.2539	groS, groL, ftsH, secA
GO:0044238	Primary metabolic process	6.480E-4	0.25	pyrI, rpsK, rplP, rpsC, rplB, ksgA, rpoC, fmt, gyrA, rpsG, fusA, rpoZ, recB, rpsR, groS, groL, ftsH, nadA, rpsI, rnhA, rpoH, infC, tmk
GO:0005515	Protein binding	3.805E-4	0.25	groL, secA
|GO:0045308
GO:0019538	Protein metabolic process	6.859E-4	0.25	rpsK, rplP, rpsC, rplB, fmt, rpsG, fusA, rpsR, groS, groL, ftsH, rpsI, infC
|GO:0006411
GO:0071704	Organic substance metabolic process	8.857E-4	0.2689	pyrI, rpsK, rplP, rpsC, rplB, ksgA, rpoC, fmt, gyrA, rpsG, fusA, rpoZ, recB, rpsR, groS, groL, ribB, ftsH, nadA, rpsI, rnhA, rpoH, infC, tmk
GO:0044260	Cellular macromolecule metabolic	0.0012	0.3325	rpsK, rplP, rpsC, rplB, ksgA, rpoC, fmt, rpsG, fusA, rpoZ, rpsR, groS, groL, rpsI, rpoH, infC
|GO:0034960	Process
GO:0001883	Purine nucleoside binding	0.0030	0.4902	fusA, groS, groL, ftsH, secA

^aThis set of genes was extracted from the full data set (673 genes and 5115 probes) using a t-test (p < 0.05).

^bGO terms that were overrepresented in the set of differentially expressed genes.

^cP-value after application of the Benjamini-Yekutelli correction (P < 0.5).