Table 1.

Summary of the studies to investigate surgical issues

Study	Issues investigated
Study 1A	Obstructions to device insertion, adhesions
Enucleated human eye (n = 14)	Location of scleral wound
	Relieving incision wound to accommodate axial length and scleral lead exit
	Verify length of array to suit human eye size
	Suture points of scleral patch
	Dimensions of scleral patch
Study 1B
PNCB measurements (n = 10)	Location of PCNB relative to optic disc was investigated
Study 2	Surgical method in humans
Whole human cadavers (n = 6)	Develop trocar design and surgical technique
	Lead orbit fixation method
	Location of scleral wound and orbital notch
	Location of scalp percutaneous pedestal wound
	Scleral patch position to allow array position beneath macula
	Angle of lead in orbit
	Suture points of scleral patch
Study 3	Expected variation in lateral canthus to pinna measurements assessed
Lateral canthus to pinna (n = 61)	Information gathered informed lead length in the final device

PNCB, posterior ciliary neurovascular bundle.