Table 4.
Plasma phospholipids
| Fatty acids (μmol/L) | HD (n = 99) | Controls (n = 160) | p-value | p* |
|---|---|---|---|---|
|
Polyunsatured ω-6: |
|
|
|
|
| Linoleic acid (18:2) |
1387.30 ± 340.15 |
1757.48 ± 289.93 |
<0.0001 |
<0.0001 |
| Γ-Linolenic acid (18:3) |
29.20 ± 14.83 |
14.79 ± 9.72 |
<0.0001 |
<0.0001 |
| Dihomo-γ-linolenic acid (20:3) |
110.68 ± 38.99 |
175.37 ± 65.68 |
<0.0001 |
<0.0001 |
| Arachidonic acid (20:4) |
437 ± 111.45 |
504.52 ± 133 |
<0.0001 |
<0.0001 |
|
Polyunsatured ω-3: |
|
|
|
|
| Α-Linolenic acid (18:3) |
18.35 ± 14.57 |
15.58 ± 9.62 |
0.4460 |
0.069 |
| Eicosapentaenoic acid (20:5) |
28.95 ± 37.49 |
39.95 ± 54.82 |
0.0081 |
0.016 |
| Docosahexaenoic acid (22:6) |
142.10 ± 67.86 |
150.51 ± 78.13 |
0.4389 |
0.508 |
|
ω-6/ω-3: |
|
|
|
|
| ARA/EPA |
28.54 ± 20 |
25 ± 17 |
0.0081 |
0.136 |
| ARA/DHA |
4.06 ± 1.53 |
3.48 ± 1.48 |
0.068 |
0.106 |
|
Ω-3 Index: |
|
|
|
|
| EPA + DHA | 179.46 ± 110.92 | 182.11 ± 111.96 | 0.832 | 0.294 |
P <0.05 is statistically significant, p* = differences between the two groups controlled for gender, age, BMI and smoke.
HD: hemodialysis. ARA: arachidonic acid. EPA: eicosapentaenoic acid. DHA=: docosahexaenoic acid.