Table 5.
Erythrocyte phospholipids
| Fatty acids (μmol/L) | HD (n = 99) | Controls (n = 160) | p-value | p* |
|---|---|---|---|---|
|
Polyunsatured ω-6: |
|
|
|
|
| Linoleic acid (18:2) |
398.83 ± 119.03 |
684.04 ± 133.4 |
<0.0001 |
<0.0001 |
| Γ- Linolenic acid (18:3) |
1.73 ± 1.09 |
0.99 ± 0.42 |
<0.0001 |
<0.0001 |
| Dihomo-γ-linolenic acid (20:3) |
45.56 ± 21.14 |
86.94 ± 35.57 |
<0.0001 |
<0.0001 |
| Arachidonic acid (20:4) |
455.66 ± 236.66 |
560.37 ± 97.66 |
<0.0001 |
0.018 |
|
Polyunsatured ω-3: |
|
|
|
|
| Α-Linolenic acid (18:3) |
0.71 ± 0.4 |
1.02 ± 0.3 |
<0.0001 |
<0.0001 |
| Eicosapentaenoic acid (20:5) |
9.74 ± 11.8 |
7.43 ± 11.47 |
0.0907 |
0.334 |
| Docosahexaenoic acid (22:6) |
132.44 ± 81.39 |
136.48 ± 42.51 |
0.0651 |
0.001 |
|
ω -6/ω-3: |
|
|
|
|
| ARA/EPA |
83.92 ± 51.43 |
133.16 ± 74.62 |
<0.0001 |
0.002 |
| ARA/DHA |
4.13 ± 4.4 |
4.48 ± 1.62 |
<0.0001 |
0.002 |
|
Ω-3 Index: |
|
|
|
|
| EPA + DHA | 192.19 ± 139.73 | 143.95 ± 50.10 | 0.0542 | 0.876 |
P <0.05 is statistically significant p* = differences between the two groups controlled for gender, age, BMI and smoke.
HD: hemodialysis. ARA: arachidonic acid. EPA: eicosapentaenoic acid. DHA=: docosahexaenoic acid.