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. Author manuscript; available in PMC: 2014 Nov 17.
Published in final edited form as: Leukemia. 2012 Jan 6;26(6):1436–1439. doi: 10.1038/leu.2011.373

Figure 2.

Figure 2

(a) Tumor engraftment studies with CD138− and CD138+ populations of 5T33 MM. (b) Drug sensitivity of CD138− and CD138+ 5T33 MM cells. Sorted populations were incubated with bz, MG132, LBH589 and 17AAG at the indicated concentrations. After 20 h, the viability was measured by the CellTiter-Glo Luminescent Viability Assay. Results are given as the percentage viability relative to control (100%). Each dot represents the result of an independent experiment. *Indicates P-value<0.05 (Mann–Whitney test). (c) Percentage CD138− cells after bz treatment in vivo measured with flow cytometry. Results shown are from five mice in each group. Differences between vehicle and bz-treated group are significant (P<0.008, Mann–Whitney test).