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. 2014 Apr 2;14:88. doi: 10.1186/1471-2229-14-88

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Copyright © 2014 Thiemann et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Negative decadic logarithms of p-values from bootstrap analysis of the 145 genomic segments across chromosomes. Negative decadic logarithms of p-values (−log(P)) from the bootstrap analysis show the significance in the increase and decrease of MPH-associated gene numbers compared to the gene number of the random gene distribution. Thresholds of 1 (blue line, p = 0.1), 1.3 (green line, p = 0.05) and 2 (red line, p = 0.01) were chosen for the identification of MPH-ASs.