Table 3. Comparison of mean quality score for each AGREE II domain by subgroup.

Subgroups	Domain(Mean ± SD)
	Scope&Purpose	Stakeholders	Rigor	Clarity	Applicability	Editorial
Year of publications
Pre-AGREE II(n = 10)	65.00±9.82	44.44±18.33	39.48±25.80	61.34±13.76	31.24±18.76	28.33±24,27
Post-AGREE II(n = 7)	57.14±20.90	46.03±22.90	45.09±31.71	67.06±18.10	30.95±22.84	32.14±33.22
p values	0.35	0.88	0.7	0.48	0.98	0.8
MD,95%CI	7.86 (−8.78, 24.49)	−1.59(−22.00,18.83)	−5.61(−34.03,22.81)	−5.67(−21.57,10.22)	0.30(−20.23,20.83)	−3.81(−32.66,25.04)
Performers
NGC&AAN(n = 7)	72.62±6.29	58.73±12.04	64.43±22.87	75.79±11.86	44.64±19.31	52.38±20.39
Others(n = 10)	54.17±15.28	35.56±18.56	25.93±18.00	55.28±11.67	21.67±14.47	14.17±19.66
p values	0.0006	0.002	0.0002	0.0004	0.008	0.0001
MD,95%CI	18.45(7.89,29.01)	23.17(8.62,37.73)	38.50(18.21,58.78)	20.52(9.13,31.90)	22.98(6.09,39.86)	38.21(18.81,57.62)
EB CPGs
Yes(n = 11)	69.19±9.25	53.54±17.66	53.98±26.54	71.97±12.14	39.58±19.59	44.32±23.37
No(n = 6)	48.15±15.28	29.63±12.99	19.44±9.81	48.61±6.51	15.63±6.81	3.47±3.14
p values	0.002	0.001	0.0001	<0.00001	0.0002	<0.00001
MD,95%CI	21.04 [7.65, 34.44]	23.91(9.18,38.63)	34.53(16.99,52.07)	23.36(14.49,32.23)	23.96(11.16,36.75)	40.85(26.81,54.88)

Notes: MD, mean difference; CI, Confidence interval; EB, evidence-based; CPGs, clinical practice guidelines; SD, standard deviation.