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. 2014 Jul 16;3(5):642–656. doi: 10.1002/mbo3.195

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© 2014 The Authors. MicrobiologyOpen published by John Wiley & Sons Ltd.

This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Contribution of paenilamicin to the antibacterial and antifungal activity of P. larvae culture supernatants. P. larvae ERIC II wild-type strain DSM25430 and mutant strain DSM25430 ΔpamA lacking paenilamicin production were grown in MYPGP medium at 30°C. Activity of culture supernatants against different bacteria (Paenibacillus alvei, Bacillus subtilis, B. licheniformis, and B. megaterium) and fungi (Saccharomyces cerevisiae, Pichia pastoris, and Fusarium oxysporum) was tested by agar diffusion assays. Neg. control: MYPGP medium.