Table 1.
Characteristics of 16 patients with definite Lyme arthritis and 5 patients with probable Lyme arthritis
|
Definite | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Age (years) | Gender | History of prior tick bite | History of prior EM | Duration of arthritis (weeks) | Joint affected | Minor flares after antibiotic treatment* | ESR (mm/h) | CRP (mg/dl) | Serum Bb IgG % of cut off at baseline | Serum Bb IgM positive test at baseline | PCR positive test for Bb in joint fluid | Intraarticular GC before antibiotic therapy |
| 46 |
Male |
Yes |
No |
3 |
Left knee |
None |
32 |
13 |
2423 |
Yes |
Yes |
Yes |
| 54 |
Male |
Yes |
No |
1 |
Left knee |
None |
55 |
89 |
700 |
No |
Yes |
Yes |
| 47 |
Female |
Yes |
No |
1 |
Right knee |
One |
45 |
1 |
1350 |
Yes |
Yes |
No |
| 68 |
Male |
Yes |
No |
104 |
Left knee |
Two |
13 |
51 |
1550 |
Yes |
Yes |
Yes |
| 65 |
Male |
Yes |
No |
1 |
Left knee |
Two |
48 |
129 |
1200 |
+/- |
Yes |
Yes |
| 70 |
Female |
Yes |
No |
7 |
Right knee |
None |
13 |
1 |
1500 |
No |
No |
No |
| 50 |
Female |
Yes |
Yes |
3 |
Left knee |
None |
9 |
2 |
2273 |
Yes |
No |
No |
| 49 |
Male |
Yes |
Yes |
1 |
Left ankle |
None |
37 |
74 |
2400 |
No |
No |
No |
| 50 |
Male |
Yes |
Yes |
1 |
Right knee |
None |
23 |
33 |
2335 |
Yes |
NA |
Yes |
| 59 |
Male |
Yes |
No |
3 |
Left knee |
One |
32 |
13 |
2423 |
Yes |
No |
No |
| 54 |
Female |
No |
No |
1.5 |
Left knee |
None |
9 |
1 |
1350 |
No |
Yes |
Yes |
| 55 |
Male |
No |
No |
12 |
Right knee |
One |
38 |
24 |
1350 |
No |
Yes |
Yes |
| 66 |
Male |
No |
No |
2.5 |
Right knee |
None |
|
67 |
NA |
NA |
Yes |
No |
| 51 |
Female |
Yes |
Yes |
12 |
Right knee |
None |
20 |
1 |
1450 |
No |
Yes |
No |
| 50 |
Female |
No |
No |
5 |
Left knee |
None |
15 |
30 |
NA |
NA |
Yes |
No |
| 47 |
Male |
No |
No |
2 |
Left knee |
None |
29 |
93 |
1300 |
+/- |
Yes |
No |
|
Probable | ||||||||||||
|
Age (years) |
Gender |
History of prior tick bite |
History of prior EM |
Duration of arthritis (weeks) |
Joint affected |
Minor flares after antibiotic treatment* |
ESR (mm/h) |
CRP (mg/dl) |
Serum Bb IgG % of cut off at baseline |
Serum Bb IgM positive test at baseline |
PCR positive test for Bb in joint fluid |
Intraarticular GC before antibiotic therapy |
| 41 |
Male |
Yes |
No |
0 |
Left ankle |
None |
8 |
53 |
2100 |
No |
No |
No |
| 80 |
Male |
No |
No |
3 |
Left knee |
† |
35 |
3 |
2550 |
No |
No |
No |
| 53 |
Female |
Yes |
No |
2 |
Both knees and several small joints in left foot (MTP and PIP-joints) |
One |
68 |
90 |
2500 |
No |
No |
No |
| 50 |
Male |
No |
No |
0 |
Right knee |
None |
68 |
132 |
1750 |
Yes |
No |
No |
| 56 | Female | Yes | Yes | 4 | Left knee | † | 15 | 1 | 1300 | Yes | No | No |
EM: Erythema migrans. ESR: Erythrocyte sedimentation rate. CRP: C-reactive protein. Bb: Borrelia burgdorferi. IgG: Immunoglobulin type G. IgM: Immunoglobulin type M. PCR: Polymerase chain reaction. GC: Glucocorticosteroids. NA: Not assessed. MTP: Metatarsophalangeal joints. PIP: Proximal interphalangeal joints.
*Defined as episodes of arthritis symptoms the patients reported the first weeks/months after antibiotic treatment.
+/- Non conclusive test.
†Concomitant osteoarthritis with recurrent episodes of joint effusion.