Skip to main content
. 2014 Nov 17;9(11):e111028. doi: 10.1371/journal.pone.0111028

Table 1. Characteristics of Acute Non-Lymphocytic Leukemia Cases and Controls in the SETIL Case-Control Study, Italy, 1998-2003.

AnLL cases Controls matched to AnLL cases All sampled controls P valuea
No. % No. % No. %
Genderd
Female 39 47.6 62 48.4 482 46.2
Male 43 52.4 66 51.6 562 52.8 Na
Age at study reference date (years)d
≤1 21 25.6 35 27.3 156 14.9
2–3 13 15.9 18 14.1 351 33.6
4–5 13 15.9 15 11.7 233 22.3
≥6 35 42.7 60 46.9 304 29.1 Na
Residence area (part of Italy)d
North (except Lombardy) 22 26.8 33 25.8 250 24.0
Lombardy 16 19.5 32 25.0 260 24.9
Center 17 20.7 23 18.0 257 24.6
South and islands 27 32.9 40 31.2 277 26.5 Na
Birth order
First born 39 47.6 68 53.1 551 52.8
Second born 31 37.8 39 30.5 379 36.3
Third born and others 12 14.6 21 16.4 113 10.8 0.49b
Birth weight (g)
<3,000 19 23.2 31 24.2 239 22.9
3,000–3,299 18 22.0 28 21.9 246 23.6
3,300–3,599 23 28.0 29 22.7 254 24.4
≥3,600 22 26.8 40 31.2 304 29.2 0.89b
Duration of breastfeeding (months)
0 12 14.6 26 20.5 232 22.3
1–3 32 39.0 32 25.2 267 25.7
4–6 19 23.2 37 29.1 233 22.4
>6 19 23.2 32 25.2 308 29.6 0.04b
Maternal age at child's birth (years)
≤24 14 17.1 23 18.1 140 13.4
25–29 25 30.5 41 32.3 382 36.7
30–34 30 36.6 44 34.6 359 34.5
≥35 13 15.8 19 15.0 160 15.4 0.65b
Birth year of the mother
<1960 15 18.3 22 17.3 145 13.9
1960–1964 27 32.9 32 25.2 328 31.5
1965–1969 22 26.8 53 31.7 373 35.8
≥1970 18 22.0 20 15.8 195 18.7 0.36b
Maternal educational level
Less than high school 46 56.1 45 35.2 400 38.4
High school 26 31.7 64 50.0 503 48.3
University 10 12.2 19 14.8 139 13.3 <0.01b
Paternal age at child's birth (years)
≤24 3 3.7 6 4.7 33 3.3
25–29 18 22.2 29 22.8 241 23.8
30–34 3 40.7 45 35.4 385 38.0
≥35 27 33.3 47 37.0 353 34.9 0.96b
Paternal educational level
Less than high school 47 58.0 54 42.2 463 44.6
High school 24 29.6 59 46.1 424 40.9
University 10 12.4 15 11.7 151 14.6 0.06b
Parental occupational exposure to benzene
Absent 80 97.6 126 98.4 1,009 96.7
Present 2 2.4 2 1.6 35 3.3 0.65c

Abbreviations: AnLL, acute non-lymphocytic leukemia; NA, not appropriate.

a

Comparison between cases and all controls sampled in the SETIL study (AnLL controls + ALL controls).

b

P values from χ2 test.

c

P values from Fisher exact test.

d

Matching variables.