Table 1.
Scope exploration.[a]
| entry | diene | aldehyde | product | yield[b] (ee) |
|---|---|---|---|---|
| 1 |
|
1 |
|
72% (85%) |
| 2 | 2 |
|
|
50 (>99%) |
| 3 | 2 |
|
|
53 (84%) |
| 4 |
|
1 |
|
71 (>99%)[c] |
| 5 |
|
1 |
|
75 (>99%)[c] |
See the Supporting Information for detailed procedures, substrate syntheses, and stereochemical determination.
Yield of isolated, purified product.
Diastereomeric products were removed by chromatography.