Figure 4.

Effect of YKS on neurogenesis in the DG of Gunn rats. YKS increased the survival of newly born neurons in the DG. (A) Survival of newly generated cells in the DG. (B–D) Representative high-magnification photomicrograph of confocal images of the area depicted by the white square in A confirmed the colocalization of both BrdU and NeuN staining. (D) Arrows indicate double-positive cells (yellow). (E) YKS increased the number of BrdU+/NeuN + cells in the DG of Gunn rats. Scale bar, 100 μm (A). Data are presented as the mean ± SEM (n = 4, respectively). *P <0.05, ANOVA followed by Bonferroni post hoc test.