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. 2014 Nov 17;9(11):e112619. doi: 10.1371/journal.pone.0112619

Figure 2. Didox has activity against AML in colony formation assays.

Figure 2

A. Didox reduced colony formation in KG1a cells. Cells were exposed to titration of Didox for 24 hours before incubation in methylcellulose (7–8 days). Mean colony formation was assessed in triplicate in 3 experiments and normalized to untreated controls. B. Didox exposure reduced colony formation in primary AML samples. Primary samples (C1–C3) were exposed to a titration of Didox for 24 hours before incubation in methylcellulose (12–14 days). Mean colony formation was assessed in triplicate in 3 experiments and normalized to untreated controls. *  = p value less than 0.05.