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. 2014 Nov 17;9(11):e112455. doi: 10.1371/journal.pone.0112455

Table 2. The proportion of rabbits with specific diseases having moderate to marked acanthocytosis or echinocytosis and mild to moderate fragmentation as compared with healthy rabbits.

Disease Clinical Diagnosis Pathologic Diagnosis AcanthocytosisMod-Mkd EchinocytosisMod-Mkd FragmentationMild-Mod
Abscess 32 18 26/50 (52%)** 14/50 (28%) 7/50 (14%)***
Bronchopneumonia 3 9 8/12 (67%)* 3/12 (25%) 1/12 (8%)**
Cellulitis§ 7 3 7/10 (70%)** 4/10 (40%) 2/10 (20%)***
Dental (non-abscess) 37 1 11/38 (29%) 14/38 (36%) 2/38 (5%)*
Dermatitis 19 5 5/24 (21%) 6/24 (25%) 1/24 (4%)
Fracture 12 2 3/14 (21%) 2/14 (14%) 0/14 (0%)
GI inflammation§ 2 9 4/11 (36%) 2/11 (18%) 1/11 (9%)**
GI stasis 25 0 5/25 (20%) 6/25 (24%) 0/25 (0%)
Neoplasia, malignant 0 22 5/22 (22%) 3/22 (14%) 2/22 (9%)**
Otitis 13 1 3/14 (21%) 3/14 (21%) 0/14 (0%)
Renal failure 7 7 4/14 (28%) 8/14 (57%)* 1/14 (7%)*
URTD 20 3 7/23 (30%) 7/23 (30%) 0/23 (0%)
Healthy 79 0 23/79 (29%) 19/79 (24%) 0/79 (0%)

*P<.05; **P<.01; ***P<.001.

Four rabbits with bronchopneumonia also had lung abscessation; 4 had confirmed sepsis.

§

Eight of 10 cases of cellulitis were septic (myiasis or bacterial); GI inflammation was septic in 7/11 cases (5 with intralesional bacteria, 1 with Coccidia, 1 with Coccidia and Giardia.

Two rabbits with renal failure also had pneumonia.

GI indicates gastrointestinal; URTD indicates upper respiratory tract disease.