. 2014 Nov 17;9(11):e112624. doi: 10.1371/journal.pone.0112624

Table 2. Average values of Young’s modulus and mean density values of spectrin-α1 expression for the change of RBCs distributions according to different radiation groups.

Group	Spectrin-α1 protein expression(mean density)			Young’s modulus(kPa)
	3d	14d	28d	3d	14d	28d
Control	1.21±0.07	1.22±0.62	1.22±0.64	12.23±1.48	12.62±1.71	12.02±1.38
C ions 2Gy	0.99±0.16^▾	1.03±0.19^▾	1.39±0.12^▾##	10.62±1.57	9.42±0.66	8.22±1.33
4Gy	0.88±0.14^▾	0.82±0.13^▾	1.10±0.18^▾##	6.02±0.60^Δ#	5.77±0.80^Δ#	5.17±0.60^Δ#
6Gy	0.75±0.15^▾	0.71±0.17^▾	0.57±0.13^▾##	5.08±0.59^Δ#	4.98±0.76^Δ#	4.72±0.74^Δ#
X-rays 4Gy	1.86±0.26^▾	2.17±0.14	1.16±0.14^##	13.05±1.84	11.09±1.77	10.16±1.35
6Gy	1.95±0.20^▾	1.36±0.17	0.95±0.17^▾##	9.20±2.05^Δ	8.40±1.91^Δ	8.82±1.17^Δ
12Gy	0.67±0.16^▾	1.11±0.27^▾	0.97±0.14^▾	5.18±0.94^Δ#	5.23±0.80^Δ#	5.21±0.66^Δ#

Errors are a standard deviation of the mean (SEM).

Note, ^Δ White triangles represents the statistical significance compared with the control group, ^#the pound sign shows the plot as time goes on and the difference mean Young’s modulus(E) between each dose group (mean ± SEM). (for 3d, Control vs C ions-2Gy, p = 0.114, p>0.05; Control vs C ions-4Gy, p = 0.000, p<0.01; Control vs C ions-6Gy, p = 0.000, p<0.01; Control vs X rays-4Gy, p = 0.200, p>0.05; Control vs X rays-6Gy, p = 0.000, p<0.01; Control vs X rays-12Gy, p = 0.000, p<0.01; for 14d, Control vs C ions-2Gy, p = 0.000, p<0.01; Control vs C ions-4Gy, p = 0.000, p<0.01; Control vs C ions-6Gy, p = 0.000, p<0.01; Control vs X rays-4Gy, p = 0.243, p>0.05; Control vs X -rays-6Gy, p = 0.000, p<0.01; Control vs X rays-12Gy, p = 0.000, p<0.01;for 28d, Control vs C ions-2Gy, p = 0.095, p>0.05; Control vs C ions-4Gy, p = 0.000, p<0.01; Control vs C ions-6Gy, p = 0.000, p<0.01; Control vs X -rays-4Gy, p = 0.871, p>0.05; Control vs X rays-6Gy, p = 0.000, p<0.01; Control vs X rays-12Gy, p = 0.000, p<0.01). But ^▾ blank triangles standards for the differences of spectrin-α1 protein average level (sp) and mean Young’s modulus (E) in different time points (mean ± SEM). The distinction was analyzed and we obtained an obvious statistical significance. ^##Double pound sign shows the plot as time goes on and the difference of protein between each dose group. (for 3d, Control vs C ions-2Gy, p = 0.000, p<0.01; Control vs C ions-4Gy, p = 0.000, p<0.01; Control vs C ions-6Gy, p = 0.000, p<0.01; Control vs X rays-4Gy, p = 0.013, p<0.05; Control vs X rays-6Gy, p = 0.000, p<0.01; Control vs X rays-12Gy, p = 0.000, p<0.01; for 14d, Control vs C ions-2Gy, p = 0.000, p<0.01; Control vs C -ions-4Gy, p = 0.000, p<0.01; Control vs C ions-6Gy, p = 0.000, p<0.01; Control vs X rays-4Gy, p = 0.000, p<0.01; Control vs X rays-6Gy, p = 0.020, p<0.05; Control vs X rays-12Gy, p = 0.023, p<0.05; for 28d, Control vs C -ions-2Gy, p = 0.010, p<0.05; Control vs C ions-4Gy, p = 0.046, p<0.05; Control vs C ions-6Gy, p = 0.000, p<0.01; Control vs X rays-4Gy, p = 0.341, p>0.05; Control vs X rays-6Gy, p = 0.000, p<0.01; Control vs X rays-12Gy, p = 0.002, p<0.01).