Figure 3.
Crystal structures of compounds 4 and 12. (A) Asymmetric units, conformation, and numbering schemes. (B) Hydrogen-bonding schemes. (C) Packing schemes showing the disruption of π···π interactions through weak CH···O and CH···π interactions (dotted lines). The crystalline pocket in 12 is marked as a yellow sphere. Some of the molecules are omitted for clarity. (D) Packing schemes. Crystalline voids can be seen in the crystal structure of 12.