Table 3. 3-(4-Substituted)aryl-4(1H)-quinolones^a.

^aDihydroartemisinin (DHA), chloroquine (CQ), and atovaquone (ATO) are internal controls for each in vitro assay: DHA, 5.5 nM W2 and 5.9 nM TM90-C2B; CQ, 229 nM for TM90-C2B and 421 nM for W2; and ATO, 1.4 nM W2 and 18.4 μM TM90-C2B.