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. 2014 Oct 31;111(45):15999–16004. doi: 10.1073/pnas.1419057111

Fig. 1.

Fig. 1.

WNK1 is required for cord formation in HUVECs and HDMECs. (A) Amounts of mRNAs encoding WNKs 1–4 in HUVECs and HDMECs relative to β-actin measured by qRT-PCR. (B and C) Changes in mRNAs encoding angiogenesis-related genes in (B) HUVECs and (C) HDMECs following depletion of WNK1 measured by qRT-PCR. (D) Effect of WNK1 depletion on cord formation by HUVECs and HDMECs. (Scale bars, 100 μm.) (E and F) Effect of siWNK1 on expression of venous and arterial markers in (E) HUVECs and (F) HDMECs. Data are mean ± SEM; n = 3 (A–C, E, and F); representative images are from three experiments (C). *P < 0.05. NS, not significant.