The probability of specific binding, for (A) particles with a single facet and (B) capsules in a bath of depletants as a function of depletant pressure. (C and D) Configurations that correspond to specific, semispecific, and nonspecific binding according to whether the binding occurs at sites of low curvature. (E and F) Singly faceted spheres and spherocylinders with various facet and cylinder sizes, respectively. Curves in A and B show the probability of specific binding at various faceting amounts; with increasing patch size (more faceting), the color goes from blue to red.