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. 2014 Oct 27;111(45):E4878–E4886. doi: 10.1073/pnas.1413582111

Fig. 7.

Fig. 7.

Bilateral renal ischemia model shows protective phenotype against I/R in Aag−/− mice. (A) Serum creatinine levels in WT and Aag−/− mice after bilateral kidney I/R (30 min of ischemia and 24 h of reperfusion); n = 3 in sham groups and n = 5–6 in I/R groups. (B) BUN in WT and Aag−/− mice after bilateral kidney I/R; n = 3 in sham groups and n = 5–6 in I/R groups. Error bars represent mean ± SEM. (C) Representative sections of kidneys from WT or Aag−/− mice 24 h after reperfusion (H&E stained). (D) WT mice displayed augmented renal tissue injury presented by higher percent of high-power fields (%HPFs) that scored 5 in our pathological examination (*P < 0.05 in comparison with corresponding WT group, n = 5 in WT I/R and n = 6 in Aag−/− I/R).