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. 2014 Nov 17;9(11):e113020. doi: 10.1371/journal.pone.0113020

Figure 1.

Figure 1

A. Percent of insulin content secreted from intact islets after static incubation at 2.8, 10, or 16.7 mM glucose with and without KP (1 µM, dark gray) or GLP-1 (20 nM, light gray). Secretion from untreated control islets is shown in white. Data are the mean ± S.E. n = 4–19. *(p<0.05) and **(p<0.001) indicate significance compared to untreated control. B, Glucose-dependent percent change in NAD(P)H from untreated intact islets (circles) and islets treated with KP (1 µM, squares) or GLP-1 (20 nM, triangles) compared to values at 2 mM glucose. Data are the mean ± S.E. n = 9–11. *p<0.01.