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. 2014 Nov 17;9(11):e113276. doi: 10.1371/journal.pone.0113276

Figure 2. In vivo tumor growth inhibition by PIT in N87-GFP flank model.

Figure 2

(A) PIT regimen. (B) PIT leads to N87-GFP flank tumor volume reduction (n = 10 mice in each treatment group; *p = 0.0456<0.05, vs. APSC), Tukey’s test with ANOVA). Treatment is indicated below the graph. (C) Repeated PIT leads to prolonged survival in N87-GFP tumor bearing mice (n = 10 mice in each treatment group, **P<0.0001), Long-rank test and Wilcoxon test). Complete tumor killing was achieved for 4 mice of 10 in the PIT group after re-treatment.