Table 1. Clinical characteristics of the subjects categorized by tHcy level at baseline.
| Variable | All subjects | tHcy<15 µmol/L | Hcy ≥15 µmol/L | P-value |
| No of subjects | 1499 | 468 | 1031 | |
| Age (y) | 61.40±11.4 | 57.71±9.91 | 64.32±12.35 | <0.001 |
| Women [n (%)] | 869 (59.97) | 338 (72.22) | 531 (51.50) | <0.001 |
| BMI (kg/m2) | 25.41±3.32 | 25.22±3.36 | 25.72±3.39 | 0.015 |
| TG (mmol/l) | 1.90±1.24 | 1.73±1.17 | 1.85±1.21 | 0.691 |
| TC (mmol/l) | 5.03±0.93 | 5.06±0.92 | 5.01±0.91 | 0.221 |
| HDL-C (mmol/l) | 1.38±0.36 | 1.47±0.31 | 1.31±0.27 | <0.001 |
| LDL-C (mmol/l) | 2.91±0.71 | 2.93±0.71 | 2.96±0.72 | 0.479 |
| tHcy (µmol/L) | 18.41±8.23 | 12.04±2.25 | 21.80±7.38 | <0.001 |
| SBP (mmHg) | 128.7±17.7 | 125.25±18.39 | 132.23±18.60 | <0.001 |
| DBP (mmHg) | 76.9±10.2 | 76.34±10.01 | 77.05±10.98 | 0.314 |
| FBG (mmol/L) | 5.39±1.65 | 5.51±1.83 | 5.26±1.61 | 0.006 |
| 2-HpBG (mmol/L) | 7.03±4.21 | 6.89±4.27 | 7.11±4.23 | 0.573 |
| eGFR (ml/min/1.73 m2) | 94.2±14.3 | 77.13±14.98 | 108.67±13.14 | <0.001 |
| UA (mmol/l) | 292.37±69.62 | 275.89±68.99 | 317.68±70.01 | <0.001 |
| Cr (mmol/l) | 64.15±19.94 | 60.92±16.01 | 69.50±18.36 | <0.001 |
| Current smoking [n (%)] | 394 (26.28) | 90 (19.23) | 304 (29.49) | <0.001 |
| Current alcohol use [n (%)] | 284 (18.94) | 61 (13.03) | 223 (21.63) | <0.001 |
| Diabetes [n (%)] | 314 (20.94) | 108 (23.07) | 206 (19.98) | 0.172 |
| History of CVD [n (%)] | 184 (12.27) | 45 (9.26) | 139 (13.48) | 0.034 |
| MetS [n (%)] | 490 (32.69) | 131 (27.99) | 359 (34.82) | <0.001 |
| Hypertension [n (%)] | 783 (52.23) | 201 (42.94) | 582 (56.45) | <0.001 |
Notes: Continuous variables (Age, BMI, TG, TC, HDL-C, LDL-C, tHcy, SBP, DBP, 2h-PBG, eGFR, UA, Cr) were expressed as mean (±SD) or median (interquartile range), and categorical variables (Women, Current smoking, Current alcohol use, Diabetes, CVD, MetS and hypertension) were expressed as counts and percentages.
Abbreviations: BMI, body mass index; TC, total cholesterol; TG, triglyceride; LDL-C, low density lipoprotein cholesterol; HDL-C, high density lipoprotein cholesterol; tHcy, total homocysteine; UA, uric acid; Cr, Creatinine; FBG, fasting blood glucose; 2-HpBG, 2-hour postprandial blood sugar; SBP, systolic blood pressure; DBP, diastolic blood pressure; eGFR, estimated glomerular filtration rate; MetS, metabolic syndrome; CVD, cardiovascular disease.