Table 2. Univariate, Stepwise multivariate linear regression and Multicollinearity analysis of tHcy levels and other parameters.

Measurement of tHcy*
Baseline tHcy* predict other parameters over 4.8 years follow-up						tHcy* and other parameters at the end of follow-up
	r	P	R	p	VIF	r	P	R	P	VIF
Sex	−0.191	<0.001	−0.067	0.005		−0.126	<0.001	−0.095	0.007
Age	0.268	<0.001	0.216	<0.001	1.229	0.265	<0.001	0.263	<0.001	1.256
BMI	0.054	0.004	0.148	0.001	2.527	0.024	0.391	0.009	0.013	2.631
Wc	0.215	<0.001	−0.201	<0.001	2.739	0.207	<0.001	−0.190	<0.001	2.906
SBP	0.063	<0.001	0.023	0.029	1.203	0.125	<0.001	0.027	0.389	1.213
DBP	0.033	0.007	0.050	0.034	1.149	0.799	0.009	0.035	0.252	1.122
TG*	0.027	0.386	0.069	0.046	1.517	−0.011	0.705	0.054	0.111	1.538
TC	−0.032	0.263	0.053	0.223	2.552	−0.069	0.015	−0.075	0.087	2.526
HDL	−0.171	<0.001	−0.123	0.005	2.620	−0.056	0.051	−0.042	0.325	2.570
LDL	0.111	<0.001	0.071	0.019	3.550	0.027	0.344	0.063	0.227	3.538
UA	0.269	<0.001	0.177	<0.047	1.449	0.216	<0.001	0.126	0.051	1.449
Cr*	0.492	<0.001	0.507	<0.001	2.535	0.365	<0.001	0.068	<0.001	2.483
FBG	−0.071	0.014	−0.070	0.019	1.078	−0.004	0.901	−0.025	0.390	1.083
e-GFR*	−0.189	<0.001	−0.082	0.007	1.545	−0.238	<0.001	−0.135	<0.001	1.502

Note: r: Pearson correlation coefficient; R: Stepwise multiple linear correlation coefficient; VIF: Variance Inflation Factor.

*: after natural logarithm transformed.

Abbreviations: tHcy, total homocysteine; BMI, body-mass index; Wc, waist circumstance; SBP, systolic blood pressure; DBP, diastolic blood pressure; TC, total cholesterol; TG, triglyceride; LDL-C, low density lipoprotein cholesterol; HDL-C, high density lipoprotein cholesterol; UA, uric acid; Cr, Creatinine; FBG, fasting blood glucose; eGFR, estimated glomerular filtration rate.