Table 3. Baseline tHcy level and the incident of MetS over 4.8 years of follow-up.
| Levels of tHcy | ||
| Incident of MetS | OR (95% CI) | P-value |
| Unadjusted | 1.61 (1.05–2.48) | 0.029 |
| Model 1 | 1.35 (0.85–2.15) | 0.203 |
| Model 2 | 1.32 (0.79–2.19) | 0.282 |
| BMIa | 1.12 (0.78–1.62) | 0.548 |
| Hypertensiona | 1.53 (1.06–2.21) | 0.024 |
| Hyperglycemiaa | 0.69 (0.43–1.09) | 0.112 |
| Dyslipidemiaa | 1.08 (0.71–1.63) | 0.716 |
Notes: Levels of tHcy were Ln transformed to normalize their distributions. Data were presented as ORs (per SD increase in LntHcy levels) and corresponding 95% CIs. In the logistic regression model, MetS was treated as the dependent variable (MetS versus NonMetS). Model1: adjusted for age, sex; Model 2: adjusted for age, sex, smoking, alcohol use, TC, LDL-C, UA, Cr, and eGFR. a: adjusted for age, sex, smoking, alcohol use, UA, Cr, and eGFR. BMI: ≥25.0 kg/M2; Hypertension: systolic blood pressure (SBP) ≥140 mmHg, or diastolic blood pressure (DBP) ≥90 mmHg, or previously diagnosed as hypertension; Hyperglycemia: fasting blood-glucose (FPG) ≥6.1 mmol/L (110 mg/dl), or 2 h postprandial glucose (PG) ≥7.8 mmol/L (140 mg/dl), or previously diagnosed as hyperglycemia; Dyslipidemia: fasting triglycerides (TG) ≥1.7 mmol/L (150 mg/dl), or fasting HDL-C<0.9 mmol/L (35 mg/dl).
Abbreviations: BMI, body mass index; TC, total cholesterol; LDL-C, low density lipoprotein cholesterol; tHcy, total homocysteine; UA, uric acid; Cr, Creatinine; eGFR, estimated glomerular filtration rate; MetS, metabolic syndrome.