Table 4. tHcy level and MetS at cross-sectional baseline.
Levels of tHcy | ||
Incident of MetS | OR (95% CI) | P-value |
Unadjusted | 1.50 (1.16–1.93) | <0.001 |
Model 1 | 1.49 (1.10–1.73) | 0.005 |
Model 2 | 1.38 (1.02–1.88) | 0.038 |
BMIa | 1.29 (1.09–1.62) | 0.002 |
Hypertensiona | 1.35 (0.89–1.21) | 0.428 |
Hyperglycemiaa | 0.87 (0.73–1.43) | 0.513 |
Dyslipidemiaa | 1.16 (0.93–1.63) | 0.108 |
Notes: Levels of tHcy were Ln transformed to normalize their distributions. Data were presented as ORs (per SD increase in LntHcy level) and corresponding 95% CIs. In the logistic regression model, MetS was treated as the dependent variable (MetS versus NonMetS). Model 1: adjusted for age, sex; Model 2: adjusted for age, sex, smoking, alcohol use, TC, LDL-C, UA, Cr, and eGFR; a: adjusted for age, sex, smoking, alcohol use, UA, Cr, and eGFR. BMI: ≥25.0 kg/M2; Hypertension: systolic blood pressure (SBP) ≥140 mmHg, or diastolic blood pressure (DBP) ≥90 mmHg, or previously diagnosed as hypertension; Hyperglycemia: fasting blood-glucose (FPG) ≥6.1 mmol/L (110 mg/dl), or 2 h postprandial glucose (PG) ≥7.8 mmol/L (140 mg/dl), or previously diagnosed as hyperglycemia; Dyslipidemia: fasting triglycerides (TG) ≥1.7 mmol/L (150 mg/dl), or fasting HDL-C <0.9 mmol/L (35 mg/dl).
Abbreviations: BMI, body mass index; TC, total cholesterol; LDL-C, low density lipoprotein cholesterol; tHcy, total homocysteine; UA, uric acid; Cr, Creatinine; eGFR, estimated glomerular filtration rate; MetS, metabolic syndrome.