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. 2014 Nov 17;9(11):e113148. doi: 10.1371/journal.pone.0113148

Table 4. tHcy level and MetS at cross-sectional baseline.

Levels of tHcy
Incident of MetS OR (95% CI) P-value
Unadjusted 1.50 (1.16–1.93) <0.001
Model 1 1.49 (1.10–1.73) 0.005
Model 2 1.38 (1.02–1.88) 0.038
BMIa 1.29 (1.09–1.62) 0.002
Hypertensiona 1.35 (0.89–1.21) 0.428
Hyperglycemiaa 0.87 (0.73–1.43) 0.513
Dyslipidemiaa 1.16 (0.93–1.63) 0.108

Notes: Levels of tHcy were Ln transformed to normalize their distributions. Data were presented as ORs (per SD increase in LntHcy level) and corresponding 95% CIs. In the logistic regression model, MetS was treated as the dependent variable (MetS versus NonMetS). Model 1: adjusted for age, sex; Model 2: adjusted for age, sex, smoking, alcohol use, TC, LDL-C, UA, Cr, and eGFR; a: adjusted for age, sex, smoking, alcohol use, UA, Cr, and eGFR. BMI: ≥25.0 kg/M2; Hypertension: systolic blood pressure (SBP) ≥140 mmHg, or diastolic blood pressure (DBP) ≥90 mmHg, or previously diagnosed as hypertension; Hyperglycemia: fasting blood-glucose (FPG) ≥6.1 mmol/L (110 mg/dl), or 2 h postprandial glucose (PG) ≥7.8 mmol/L (140 mg/dl), or previously diagnosed as hyperglycemia; Dyslipidemia: fasting triglycerides (TG) ≥1.7 mmol/L (150 mg/dl), or fasting HDL-C <0.9 mmol/L (35 mg/dl).

Abbreviations: BMI, body mass index; TC, total cholesterol; LDL-C, low density lipoprotein cholesterol; tHcy, total homocysteine; UA, uric acid; Cr, Creatinine; eGFR, estimated glomerular filtration rate; MetS, metabolic syndrome.