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. 2014 Nov 17;9(11):e113250. doi: 10.1371/journal.pone.0113250

Figure 4. PLX Induces Double-stranded DNA Breaks in Cancer Cells.

Figure 4

TUNEL labeling was used to detect DNA fragmentation. Following PLX and VP16 (as a positive control for DNA damage) treatment, cells were labelled with DNA staining solution and quantified by image-based cytometry. Treated cells were compared to the control untreated cell sample. (****P<0.0001).