Table 2.
Combined ACE I/D and ACTN3 R577X genotype frequencies among swimmers and control subjects
| Group | II | ID | DD | ||||||
|---|---|---|---|---|---|---|---|---|---|
|
| |||||||||
| RR | RX | XX | RR | RX | XX | RR* | RX | XX | |
| LDS (n=49) | 5 (10.9) | 9 (14.1) † | 7 (43.8)† | 8 (6.3) | 17 (14.9)† | 0 (0)† | 2 (2.9) | 1 (1.4) | 0 (0) |
| SDS (n=147) | 11 (23.9) | 17 (26.6) | 2 (12.5) | 41 (32.0) | 24 (21.1) | 15 (29.4) | 19 (27.9) | 15 (20.6) | 3 (20.0) |
| Control (n=379) | 30 (65.2) | 38 (59.4) | 7 (43.8) | 79 (61.7) | 73 (64.0) | 36 (70.6) | 47 (69.1) | 57 (78.1) | 12 (80.0) |
LR Chi-square 50.6, df=16, p<0.0001; LDS – long distance swimmers, SDS – short distance swimmers;
*
reference genotype (DD/RR) for comparisons;
†
significant when compared with reference genotype relative to the control group