Table 3.
Combined genotype frequencies among swimmers and control subjects assuming ACE/ACTN3 dominant models and ACE/ACTN3 recessive models
| Group | ACE and ACTN3 dominant models combinations | ACE and ACTN3 recessive models combinations | ||||||
|---|---|---|---|---|---|---|---|---|
|
| ||||||||
| DD/RR* | DD/XX+RX | II+ID/RR | II+ID/XX+RX | ID+DD/RR+RX* | ID+DD/XX | II/RR+RX | II/XX | |
| LDS (n=49) | 2 (2.9) | 1 (1.1) | 13 (7.5) | 33 (13.5)† | 28 (7.3) | 0 (0) | 14 (12.7) | 7 (43.8)† |
| SDS (n=147) | 19 (27.9) | 18 (20.5) | 52 (29.9) | 58 (23.7) | 99 (25.9) | 18 (27.3) | 28 (25.5) | 2 (12.5) |
| Control (n=379) | 47 (69.1) | 69 (78.4) | 109 (62.6) | 154 (62.9) | 256 (66.8) | 48 (72.7) | 68 (61.8) | 7 (43.8) |
Dominant models – LR Chi-square 23.8, df=6, p=0.0006; Recessive models – LR Chi-square 29.1, df=6, p=0.00006, LDS – long distance swimmers, SDS – short distance swimmers;
*
model-specific reference genotype for comparisons;
†
significant when compared with reference genotype relative to the control group