Table 4.
Characteristics of the mechanically ventilated patients a
| Preintervention ( n = 2,446) | Postintervention ( n = 2,405) | P -value | |
|---|---|---|---|
| Characteristics | October 2010 to September 2011 | October 2011 to October 2012 | |
| Age, yr, mean ± SD | 62.37 ± 19 | 61.99 ± 18 | 0.467 |
| Male, n (%) | 1,306 (53.4) | 1,275 (53.0) | 0.792 |
| BMI, kg/m2, mean ± SD | 26.7 ± 6 | 26.7 ± 6 | 0.726 |
| SAPS III score, mean ± SD | 52.65 ± 19 | 51.44 ± 20 | 0.031 |
| Charlson index score, median (IQR) | 1 (0; 2) | 1 (0; 2) | 0.181 |
| Admission type, n (%) | 0.119 | ||
| Medical | 1,547 (63.2) | 1,452 (60.4) | |
| Elective surgical | 767 (31.4) | 811 (33.7) | |
| Emergency surgical | 132 (5.4) | 142 (5.9) | |
| Diagnosis category, n (%) | |||
| Cardiovascular | 219 (9.0) | 208 (8.6) | 0.708 |
| Sepsis | 505 (20.6) | 548 (22.8) | 0.071 |
| Neurological | 284 (11.6) | 276 (11.5) | 0.883 |
| Respiratoryb | 303 (12.4) | 182 (7.6) | <0.001 |
| Orthopedic surgery | 28 (1.1) | 31 (1.3) | 0.647 |
| Neurosurgery | 63 (2.6) | 47 (2.0) | 0.146 |
| Thoracic surgery | 24 (1.0) | 31 (1.3) | 0.311 |
| Cardiac surgery | 545 (22.3) | 627 (26.1) | 0.002 |
| Resources during ICU, n (%) | |||
| RRT | 174 (7.1) | 185 (7.7) | 0.441 |
| Vasopressors | 1,321 (54) | 1,436 (59.7) | <0.001 |
| Noninvasive ventilation | 639 (26.1) | 612 (25.4) | 0.590 |
| Mechanical ventilation, n (%) | |||
| During ICU stay | 2,446 (100) | 2,405 (100) | – |
| At ICU admission | 1,677 (68.6) | 1,673 (69.6) | 0.450 |
| Tracheotomy | 314 (12.8) | 237 (9.9) | 0.001 |
| Length of mechanical ventilation | |||
| Mean ± SD | 3.91 ± 6.2 | 3.15 ± 4.6 | <0.001 |
| Median (IQR) | 1 (1; 4) | 1 (1; 3) | 0.001 |
| MV >24 hr | 1,007 (41.1) | 971 (40.2) | 0.510 |
| 28 ventilator-free days | |||
| Mean ± SD | 16.07 ± 12.2 | 18.33 ± 11.6 | <0.001 |
| Median (IQR) | 24 (0; 27) | 26 (0; 27) | <0.001 |
| ICU LOS, days | |||
| Mean ± SD | 8.87 ± 11.9 | 7.46 ± 9.2 | <0.001 |
| Median (IQR) | 5 (2; 12) | 4 (2; 10) | <0.001 |
| Total hospital LOS, days | |||
| Mean ± SD | 23.75 ± 33.7 | 23.80 ± 31.3 | 0.961 |
| Median (IQR) | 13 (6; 28) | 13 (6; 27) | 0.707 |
| Mortality, % (95% CI) | |||
| ICU mortality | 36.8% (35.0; 38.8) | 29.6% (27.8; 31.4) | <0.001 |
| Hospital mortality | 45.4% (43.5; 47.4) | 38.1% (36.2; 40.1) | <0.001 |
aBMI, Body mass index; ICU, Intensive care unit; MV, Mechanical ventilation; RRT, Renal replacement therapy. bRespiratory diagnosis except pneumonia.