Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2014 Nov 11;12:341. doi: 10.1186/1477-7819-12-341

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© Xu et al.; licensee BioMed Central Ltd. 2014

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

PMC Copyright notice

Osteosarcoma arising from the left distal femur in a 15-year-old boy. (A,B) Before chemotherapy. (A) Magnetic resonance imaging (MRI) scan of the tumor obtained before neoadjuvant chemotherapy; arrows show lesions in longest diameter. (B) Tumor cells (hematoxylin and eosin (H&E), original magnification × 40). (C,D) After chemotherapy. (C) MRI scan of the same tumor after chemotherapy showed that there was no tumor extension into the epiphysis. Extensive calcification and the significantly reduced lesion (arrows, the sum of the longest diameter ≥30% reduction) indicated a good response to therapy. (D) Significant tumor cell degeneration and necrosis (H&E, original magnification × 40).