Table 4.
Top Cancer-Relevant KEGG Pathways in KAT6A SUM-52 Knockdown Cells.
| SUM-52 |
|||
|---|---|---|---|
| pSize | P value | FDR | |
| Wnt signaling pathway | 143 | 0.00004 | 0.001415 |
| PI3K-Akt signaling pathway | 347 | 0.000010 | 0.002186 |
| Hippo signaling pathway | 156 | 0.000008 | 0.002186 |
| MAPK signaling pathway | 260 | 0.000086 | 0.006011 |
| Insulin signaling pathway | 140 | 0.000205 | 0.006011 |
| Calcium signaling pathway | 183 | 0.000184 | 0.010928 |
| Hedgehog signaling pathway | 51 | 0.000932 | 0.011069 |
| ErbB signaling pathway | 88 | 0.000944 | 0.014924 |
pSize indicates the number of genes in the KEGG pathway.
P value indicates the probability of obtaining the number of screen hits in the pathway by chance alone.
FDR indicates the global probability corrected for false discovery rate of obtaining the indicated number of pathway hits by chance alone.