Table 3.
Percentage reduction of worm burden in mice infected with cercariae pre-treated with aqueous extract of G. lotoides fruits
|
Worm burden (Mean ± SD) | |||||
|---|---|---|---|---|---|
| Treatments |
Male |
Female |
Couple |
Total |
Total worm burden reduction (%) |
| M ± SD | M ± SD | M ± SD | M ± SD | ||
| Infected control |
2.4 ± 0.418 |
3.2 ± 0.636 |
1.2 ± 0.398 |
6.8 ± 0.398 |
- |
| 3. 7 mg/L |
1.4 ± 0.328 |
2.2 ± 0.48 |
0.8 ± 0.35 |
4.4 ± 0.5 |
35.3% |
| 11.6 mg/L |
1.8 ± 0.79* |
0.8 ± 0.21* |
0.4 ± 0.17* |
3 ± 0.247* |
55.9% |
| 18.7 mg/L | 0.4 ± 0.08** | 0.2 ± 0.09** | 0.0 ± 0.0** | 0.6 ± 0.178** | 91.2% |
Note Results are expressed as mean ± SD of the mean of five observations. *Indicates the level of significance of the experimental mice compared to the infected control. No statistical significant difference was obtained at 3.7 mg/L (P > 0.05), *statistically significant at 11.6 mg/L (P < 0.05) and **highly significant difference at 18.7 mg/L (P < 0.001) compared with infected control.