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. 2014 Apr 5;7:27. doi: 10.1186/1756-6606-7-27

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Copyright © 2014 Liu and Zhuo; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Spatial analysis of LTD distribution in the ACC. (A and B) Polygonal diagrams of the channels that were activated in the baseline (blue, A) and that showed LTD (red, B) in 6 slices from 5 mice. Vertical lines denote the specific layers in the ACC slice. Overlapped blue regions denote frequently activated channels, while overlapped red regions indicate the channels that are most likely to undergo LTD. (C and D) Similar as (A and B) but with LFS delivered in the presence of AMG9810 (n = 6 slices/6 mice). It is evident that the spatial distribution of LTD-showing channels is not altered by the TRPV1 antagonism.