Table 4.
Differential expression (fold change ≥ 1.5; P ≤ 0.01) of innate immune-related genes between LRarray and HRarray fibroblast cultures following exposure to LPS (100 ng/ml; 8 h). Data were obtained by microarray analysis and represent mean fold change of three replicated experiments.
| Probe ID | Gene symbol | Fold change |
|---|---|---|
| Genes down-regulated in low responder relative to high responder | ||
| Bt.2408.1.S1_s_at | CCL2 | −1.5 |
| Bt.24326.1.S1_at | CCL11 | −2.0 |
| Bt.26655.1.S1_at | CCL19 | −1.6 |
| Bt.9560.1.S1_at | CCL20 | −4.2 |
| Bt.13130.1.S1_at | CD40 | −1.8 |
| Bt.50.1.S1_at | CD8A | −1.7 |
| Bt.18368.1.S1_at | CXCL11 | −1.5 |
| Bt.7671.1.S1_at | IFITM3 | −1.5 |
| Bt.5508.1.S1_at | IFNAR2 | −1.7 |
| Bt.3686.1.S1_at | IL6 | −2.5 |
| Bt.155.1.S1_at | IL8 | −3.6 |
| Bt.4675.1.S1_a_at | MX1 | −2.2 |
| Bt.20891.1.S1_at | OAS2 | −2.0 |
| Bt.12148.1.S1_at | PPARGC1A | −1.6 |
| Bt.357.1.S1_at | S100A12 | −1.5 |
| Bt.5970.1.S1_a_at | S100A2 | −2.0 |
| Bt.278.1.S1_at | SAA3 | −5.3 |
| Bt.8945.1.S1_at | TLR2 | −1.9 |
| Bt.12298.1.S1_at | TLR3 | −1.5 |
| Bt.9030.1.S1_at | TLR4 | −2.2 |
| Bt.26969.1.A1_at | TNFAIP8L3 | −1.5 |
| Bt.12694.1.S1_at | TNFRSF21 | −2.3 |
| Genes up-regulated in low responder relative to high responder | ||
| Bt.5392.1.S1_at | CXCL12 | 1.9 |
| Bt.7425.1.S1_at | IL1F6 | 3.0 |
| Bt.15910.1.S1_at | IL1RN | 2.9 |
| Bt.4199.1.S1_at | PPARG | 1.9 |
| Bt.456.1.S1_at | SST | 4.3 |