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. Author manuscript; available in PMC: 2014 Nov 18.
Published in final edited form as: Circulation. 2009 Sep 28;120(15):1482–1490. doi: 10.1161/CIRCULATIONAHA.109.848994

Table 4.

Preintervention Variables Associated With Postnatal Biventricular or Single-Ventricle Outcome After In Utero Aortic Valvuloplasty

Biventricular Outcome
(n=17)
All Attempted Interventions, Single-Ventricle Outcome (n=51) Technically Successful Interventions, Single-Ventricle Outcome
(n=33)
P
Gestational age, wk 23.9±2.6 24.0±2.6 23.7±2.0 0.95, 0.68
Aortic annulus diameter Zscore −2.2±0.8 −2.7±0.9 −2.7±0.9 0.03, 0.02
Ascending aorta diameter Z score 0.6±1.9 −1.4±1.8 −1.2±1.6 <0.001,* 0.002
LV long-axis dimension Zscore 2.1±1.5 −0.2±1.8 0.3±1.6 <0.001, <0.001
LV short-axis dimension Zscore 3.6±2.7 2.4±2.3 2.7±2.6 0.09,* 0.28
LV sphericity 0.62±0.09 0.72±0.13 0.69±0.12 0.004, 0.04
MV annulus diameter Zscore −0.6±1.3 −1.6±1.3 −1.6±1.1 0.009,* 0.01
RV long-axis dimension Zscore 1.7±1.8 1.1±1.2 1.4±1.1 0.13, 0.46
Female, n (%) 7 (41) 9 (18) 7 (21) 0.06, 0.14
“High” LV pressure, n (%) 13 (76) 15 (29) 10 (30) 0.006, 0.004
Moderate or severe MR, n (%) 10 (59) 27 (53) 18 (54) 0.67, 0.77
MV inflow time (msec) 124±38 115±40 118±45 0.43, 0.62
MV inflow time Z score −2.9±1.6 −3.2±1.7 −3.1±1.9 0.47,* 0.67
Restrictive PFO/intact atrial septum, n (%) 4 (24) 4 (8) 2 (6) 0.10, 0.16
Acute postdilation AR (moderate or greater), n (%) 5 (29) NA 14 (42) 0.45

PFO indicates patent foramen ovale. Includes patients with a biventricular outcome from birth or after intermediate univentricular palliation. Biventricular outcome vs single-ventricle outcome *including or †excluding technically unsuccessful interventions. Data are presented as mean±SD unless otherwise indicated.