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. 2014 Nov 18;5:618. doi: 10.3389/fmicb.2014.00618

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Copyright © 2014 Bull and Gill.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Co-dynamics of bacteria and phage in a model with a constant washout rate. (A) shows dynamics with an adsorption rate of 10^-9 mL/min, (B) with an adsorption rate of 10^-10 mL/min. Parameters are otherwise the same between (A) and (B). The higher adsorption leads to better killing of the cells. As is typical in these models when adsorption rate is high, densities fluctuate because phage decline (due to washout) after cell density has been depressed, and once phage density declines, bacterial densities rebound until phage catch up. However, with a mere 10-fold decline in adsorption rate, phage can grow but fail to depress bacterial densities substantially. The model is based on differential equations similar to those in Bull et al. (2014).