Table 2.
Biochemical Parameters of the Patients
| Primary HLH | Secondary HLH | p value | |
|---|---|---|---|
| Mean (Min-Max) | Mean (Min-Max) | ||
| AST (5–45 U/L) | 396 ± 200 (48–4138) | 272 ± 87 (15–1300) | p>0.05 |
| ALT (5–45U/L) | 286 ± 202 (1–4120) | 152 ± 61 (13–1082) | p>0.05 |
| Total bilirubin (<2mg/dl) | 3 ± 0.6 (0.3–7.5) | 0.6 ± 0.09 (0.2–1.7) | p=0.006 |
| Direct bilirubin (<0.2 mg/dl) | 2.3 ± 0.5 (0–6.4) | 0.4 ± 0.08 (0.1–1.6) | p=0.044 |
| Albumin (3.5–5.2 g/dl) | 2.7 ± 1.1 (1.4–3.7) | 3 ± 0.14 (2–4.5) | p>0.05 |
| LDH (100–295 U/L) | 793 ±169 (110–2895) | 1503 ± 468 (321–7190) | p>0.05 |
| Na (133–146 mmol/L) | 128 ± 1.1 (116–136) | 130 ± 0.8 (125–138) | p>0.05 |
| K (3.4–5.1 mmol/L) | 4.2 ± 0.1 (3.5–5) | 4 ± 0.1 (2.6–5) | p>0.05 |
| P (4.5–5.5 mg/dl) | 3.5 ± 0.28 (2–7.5) | 3.6 ± 0.4 (1.7–7.8) | p>0.05 |
| Ca (8.8–10.8 mg/dl) | 8.1 ± 0.3 (7–9.5) | 8 ± 0.2 (5.9–9.6) | p>0.05 |
| Sedimentation rate (4–20 mm/hour) | 23 ± 5 (2–64) | 39.7 ± 7.9 (1–115) | p>0.05 |
| C-reactive protein (0–0.5 mg/dl) | 46 ± 10 (4–185) | 104 ± 16.9 (3–197) | p=0.017 |
| Triglyceride (mg/dl) | 397±47 (120–936) | 364±76 (47–1350) | p>0.05 |
| Ferritin (ng/ml) | 11500 ±3282 (405–56124) | 11200±2895 (1574–40000) | p>0.05 |