Table 3.
Median survival time of glioma-bearing mice models in different therapeutic groups
| Group | Median (days) | Standard error | 95% confidence interval | IST |
|---|---|---|---|---|
| Saline | 36 | 6.3 | 23.6–48.4 | |
| Taxol | 45 | 4.7 | 35.7–54.3 | 25% |
| PTX NPs | 48 | 0.8 | 46.5–49.5a,b | 33.3% |
| PTX TNPs | 60 | 2.3 | 55.4–64.6a–c | 66.7% |
Notes:
a
P<0.01 compared with saline group
b
P<0.05 compared with Taxol group
c
P<0.01 compared with PTX NP group.
Abbreviations: IST, the increases in survival times (%) compared to control; NPs, nanoparticles; CREKA, cysteine–arginine–glutamic acid–lysine–alanine; TNPs, CREKA-conjugated NPs; PTX, paclitaxel.