A; In the PAB group, the expression of pro-apoptotic Bax was significantly greater than in the control group at 8 weeks, beginning at 4 weeks after PAB. The ratio of Bcl-2/Bax was significantly lower in the PAB group after 6 and 8 weeks.
B,C; The expression of active caspase-3 and total caspase-9 was also higher in the PAB group after 6 and 8 weeks. *p<0.05, and †p<0.01 versus the control group.