Table I.
Production of fetuses after single blastomere biopsy and sham biopsy.
| No. of oocytes inseminated (no experiments) | No. of 2-cell embryos (%)a | No. of 4-cell embryos (%)b | No. of 4-cell embryos biopsied | No. of 4-cell embryos sham biopsied (control) | No. of embryos survived biopsy (%)c | No. of embryos developed to M/EB (%)d | No. of M/EB transferred (No of females) | No. of fetuses at Day 18 (%)e | No. of resorption sites at Day 18 (%)e | No. of implants at Day 18 (%)e |
|---|---|---|---|---|---|---|---|---|---|---|
| 264 (4) | 251 (95) | 248 (98.8) | 103 | n/a | 102 (99) | 102 (100) | 97 (7) | 24 (25) | 37 (38) | 61 (63) |
| n/a | 88 | 85 (97) | 85 (100) | 70 (6) | 16 (23) | 25 (36) | 41 (59) |
M/EB, morula/early blastocyst stage. Two females from control group failed to achieve pregnancy, most likely due to no pseudopregnancy. The proportion of fetuses remained similar between biopsied and control groups regardless whether or not two non-pregnant females were included in data analysis but more resorption sites per female were noted in the control group when they were excluded. These data were shown as Supplementary data, Table SI in Sugawara et al. (2012).
aPercentage calculated from oocytes inseminated.
bPercentage calculated from 2-cell embryos.
cPercentage calculated from 4-cell embryos biopsied.
dPercentage calculated from survived biopsied or sham-biopsied 4-cell embryos.
ePercentage calculated from (control) M/EB transferred.